Isotretinoin Prescription: Quick Facts and FAQs

Isotretinoin is a powerful drug used for severe acne that hasn’t responded to other treatments. Because it can cause serious side effects, doctors only prescribe it when the benefits outweigh the risks. If you’re thinking about it, you’ll want to know how you actually get the prescription, what to expect, and how to stay safe.

First off, you need a skin‑care doctor or a dermatologist who can evaluate your acne. They’ll ask about your medical history, any recent pregnancies, and other medicines you’re taking. This check‑up is crucial because isotretinoin can’t be used with certain drugs or conditions.

When the doctor decides you’re a good candidate, they’ll write a prescription for a specific dose. The dose is usually based on your weight and the severity of your acne. Most people start with a low dose and increase it over a few weeks. The goal is to clear the skin while keeping side effects as mild as possible.

In the UK, you can’t just pick up isotretinoin at a pharmacy without a prescription. You’ll need a paper or electronic script from a qualified prescriber. Online pharmacies are allowed, but they must be GPhC‑registered and require the same prescription details.

How to Get an Isotretinoin Prescription in the UK

Step 1: Book an appointment with a dermatologist or a GP who can refer you to a skin specialist. Bring a list of any medicines you already use and any past medical issues.

Step 2: During the visit, the doctor will assess your acne and may run blood tests to check liver function and cholesterol. These tests are a routine part of isotretinoin monitoring.

Step 3: If you’re approved, the doctor writes the prescription. You’ll receive a paper copy or an e‑script sent directly to a registered pharmacy.

Step 4: Pick up the medication at the pharmacy. The pharmacist will double‑check the prescription and may give you a brief safety talk.

Step 5: Follow up. You’ll need regular blood tests, usually every month, to make sure your liver and cholesterol stay in a safe range. The doctor may adjust the dose based on those results.

Key Tips for Safe Use

Take isotretinoin exactly as prescribed. Missing doses can reduce effectiveness and increase side effects.

Never share the medication with anyone else. It’s not a one‑size‑fits‑all drug.

Use a good moisturizer and sunscreen. Isotretinoin dries out skin and makes it more sensitive to sunlight.

Avoid vitamin A supplements while on isotretinoin. Too much vitamin A can cause toxicity.

Report any severe side effects right away—especially signs of depression, persistent headaches, or vision changes. Early detection keeps problems manageable.

Most people finish a treatment course in 4‑6 months and see lasting skin improvement. After finishing, you’ll have a final check‑up to confirm everything is back to normal.

Looking for more detail? Browse the articles below to learn about isotretinoin dosing, side‑effect management, and real‑world patient stories.